Comparison

MeBIO European Partner

Item no. HY-103221-5mg
Manufacturer MedChem Express
CASRN 667463-95-8
Amount 5 mg
Quantity options 100 mg 10 mM/1 mL 10 mg 1 ea 1 mg 25 mg 50 mg 5 mg
Category
Type Inhibitors
Specific against other
Purity 98.0
Formula C17H12BrN3O2
Citations [1]Meijer L, et al. GSK-3-selective inhibitors derived from Tyrian purple indirubins. Chem Biol. 2003 Dec;10(12):1255-66.
[2]Knockaert, et al. Independent actions on cyclin-dependent kinases and aryl hydrocarbon receptor mediate the antiproliferative effects of indirubins. Oncogene 23.25 (2004): 4400-4412.
Smiles O=C1N(C)C2=C(C=CC(Br)=C2)/C1=C3NC4=C(C=CC=C4)C/3=N\O
ECLASS 10.1 32160490
ECLASS 11.0 32160490
UNSPSC 12000000
Shipping condition Room temperature
Available
Manufacturer - Type
Reference compound
Manufacturer - Applications
COVID-19-anti-virus
Manufacturer - Targets
Aryl Hydrocarbon Receptor; CDK; GSK-3
Shipping Temperature
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Product Description
MeBIO is a potent AhR (aryl hydrocarbon receptor) agonist, with IC50 of 44 μM (GSK-3) and 55 μM (CDK1/cyclin B), respectively[1].
Manufacturer - Research Area
Others
Solubility
DMSO : 14.71 mg/mL (ultrasonic; warming; heat to 60°C)
Manufacturer - Pathway
Cell Cycle/DNA Damage; Immunology/Inflammation; PI3K/Akt/mTOR; Stem Cell/Wnt
Isoform
CDK1; CDK5; GSK-3
Clinical information
No Development Reported

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 5 mg
Available: In stock
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