Comparison

DY268 European Partner

Manufacturer MedChem Express
Category
Type Inhibitors
Specific against other
Amount 100mg
Item no. HY-110267-100mg
CASRN 1609564-75-1
Available
Product Description
DY268 is a farnesoid X receptor (FXR) antagonist (IC50=7.5 nM in a time-resolved FRET assay). It inhibits FXR transactivation in a cell-based assay with an IC50 value of 468 nM.
StorageTemperature
Powder -20°C 3 years, 4°C 2 years; In solvent -80°C 6 months, -20°C 1 month
Applications
Metabolism-sugar/lipid metabolism
Formula
C30H32N4O5S
References
[1].Yu DD, Lin W, Forman BM, Chen T. Identification of trisubstituted-pyrazol carboxamide analogs as novel and potent antagonists of farnesoid X receptor. Bioorg Med Chem. 2014 Jun 1; 22(11):2919-38.
MolecularWeight
560.66
Research Area
Metabolic Disease
Solubility
DMSO : 100 mg/mL (178.36 mM; Need ultrasonic)
Target
FXR
Pathway
Metabolic Enzyme/Protease

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

Amount: 100mg
Available: In stock
available

Delivery expected until 4/6/2023 

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