DY268

Manufacturer	MedChem Express
Category	Inhibitors
Type	Inhibitors
Specific against	other
Amount	100mg
Item no.	HY-110267-100mg
CASRN	1609564-75-1
Available
Product Description	DY268 is a farnesoid X receptor (FXR) antagonist (IC50=7.5 nM in a time-resolved FRET assay). It inhibits FXR transactivation in a cell-based assay with an IC50 value of 468 nM.
StorageTemperature	Powder -20°C 3 years, 4°C 2 years; In solvent -80°C 6 months, -20°C 1 month
Applications	Metabolism-sugar/lipid metabolism
Formula	C30H32N4O5S
References	[1].Yu DD, Lin W, Forman BM, Chen T. Identification of trisubstituted-pyrazol carboxamide analogs as novel and potent antagonists of farnesoid X receptor. Bioorg Med Chem. 2014 Jun 1; 22(11):2919-38.
MolecularWeight	560.66
Research Area	Metabolic Disease
Solubility	DMSO : 100 mg/mL (178.36 mM; Need ultrasonic)
Target	FXR
Pathway	Metabolic Enzyme/Protease

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Amount: 100mg

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Delivery expected until 4/6/2023

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