DY268

Manufacturer	MedChem Express
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Amount	10 mg
Item no.	HY-110267-10mg
CASRN	1609564-75-1
eClass 6.1	30220300
eClass 9.0	32160605
Available
Product Description	DY268 is a farnesoid X receptor (FXR) antagonist (IC50=7.5 nM). It inhibits FXR transactivation in a cell-based assay with an IC50 value of 468 nM. DY268 can be used in the study of drug-induced liver injury (DILI)[1][2].
StorageTemperature	-20°C, 3 years; 4°C, 2 years (Powder)
Shipping	Room Temperature
Manufacturers Applications	Metabolism-sugar/lipid metabolism
MolecularWeight	560.66
Clinical_Information	No Development Reported
Manufacturers Research_Area	Metabolic Disease
Solubility	DMSO : 50 mg/mL (ultrasonic; warming; heat to 60°C)
Manufacturers Target	FXR
Pathway	Metabolic Enzyme/Protease
Manufacturers Product type	Reference compound

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