Comparison

P53R3 European Partner

Manufacturer MedChem Express
Category
Type Inhibitors
Specific against other
Amount 10mg
Item no. HY-122578-10mg
CASRN 922150-12-7
Available
Product Description
P53R3 is a potent p53 reactivator and restores sequence-specific DNA binding of p53 hot spot mutants, including p53R175H, p53R248W and p53R273H. P53R3 induces p53-dependent antiproliferative effects with much higher specificity than PRIMA-1. P53R3 enhances the recruitment of wild-type p53 and p53M237I to several target gene promoters. P53R3 strongly enhances the mRNA, total protein and cell surface expression of the death receptor death receptor 5 (DR5). P53R3 is used for cancer research.
StorageTemperature
Please store the product under the recommended conditions in the Certificate of Analysis.
Applications
Cancer-programmed cell death
Formula
C32H35Cl2N5O2
References
[1].Alejandro Parrales, et al. Targeting Oncogenic Mutant p53 for Cancer Therapy. Front Oncol
MolecularWeight
592.56
Research Area
Cancer
Target
MDM-2/p53
Pathway
Apoptosis

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

Amount: 10mg
Available: In stock
available

Delivery expected until 4/13/2023 

Compare

Add to wishlist

Request delivery time

Ask a technical question

Submit a bulk request

Questions about this Product?
 
Close