Comparison

P53R3 European Partner

Manufacturer MedChem Express
Category
Type Inhibitors
Specific against other
Amount 50 mg
Item no. HY-122578-50mg
CASRN 922150-12-7
eClass 6.1 30220300
eClass 9.0 32160605
Available
Product Description
P53R3 is a potent p53 reactivator and restores sequence-specific DNA binding of p53 hot spot mutants, including p53R175H, p53R248W and p53R273H. P53R3 induces p53-dependent antiproliferative effects with much higher specificity than PRIMA-1. P53R3 enhances the recruitment of wild-type p53 and p53M237I to several target gene promoters. P53R3 strongly enhances the mRNA, total protein and cell surface expression of the death receptor death receptor 5 (DR5). P53R3 is used for cancer research[1].
StorageTemperature
4°C (Powder, stored under nitrogen)
Shipping
Room Temperature
Manufacturers Applications
Cancer-programmed cell death
Molecular Weight
592.56
Clinical Information
No Development Reported
Solubility
DMSO : ≥ 100 mg/mL
Pathway
Apoptosis
Manufacturers Product type
Reference compound

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 50 mg
Available: In stock
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