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Adenosine dialdehyde

Adenosine dialdehyde

Item no.	HY-123055-25mg
Manufacturer	MedChem Express
CASRN	34240-05-6
Amount	25 mg
Quantity options	10 mM/1 mL 10 mg 25 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	99.00
Formula	C10H11N5O4
Citations	[1]G V Madhavan, et al. Synthesis and antiviral evaluation of 6'-substituted aristeromycins: potential mechanism-based inhibitors of S-adenosylhomocysteine hydrolase. J Med Chem [2]B Bostrom, et al. Inhibitory effect of adenosine dialdehyde on in situ murine neuroblastoma growth.Cancer Res. 1988 Nov 1;48(21):5933-6. [3]V Ramakrishnan, et al. Adenosine dialdehyde and neplanocin A: Potent inhibitors of S-adenosylhomocysteine hydrolase in neuroblastoma N2a cells. Neurochem Int. 1987;10(4):423-31.
Smiles	O=CC(OC(C=O)CO)N1C=NC2=C(N)N=CN=C12
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	34240-05-6
Similar products	34240-05-6
Shipping condition	Cool pack
Available
Manufacturer - Type	Reference compound
Manufacturer - Applications	Cancer-programmed cell death
Manufacturer - Targets	Nucleoside Antimetabolite/Analog
Shipping Temperature	Blue Ice
Storage Conditions	-20°C (Powder, sealed storage, away from moisture)
Molecular Weight	265.23
Product Description	Adenosine dialdehyde, a purine nucleoside analogue, is a potent inhibitor of S-Adenosylhomocysteine hydrolase (SAHH) (Ki=3.3 nM)[1]. Adenosine Dialdehyde exhibits potent anti-tumor activity in vivo and can be used for the cancer research[1][2].
Manufacturer - Research Area	Cancer
Solubility	DMSO : 10 mg/mL (ultrasonic)
Manufacturer - Pathway	Cell Cycle/DNA Damage
Clinical information	No Development Reported

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HY-123055-25mg-safety-datasheet.pdf