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Adenosine dialdehyde

Adenosine dialdehyde

Manufacturer	MedChem Express
Category	Inhibitors
Type	Inhibitors
Specific against	other
Amount	5mg
Item no.	HY-123055-5mg
CASRN	34240-05-6
Available
Product Description	Adenosine dialdehyde, a purine nucleoside analogue, is a potent inhibitor of S-Adenosylhomocysteine hydrolase (SAHH) (Ki=3.3 nM). Adenosine Dialdehyde exhibits potent anti-tumor activity in vivo and can be used for the cancer research.
StorageTemperature	Pure form -20°C 3 years, 4°C 2 years; In solvent -80°C 6 months, -20°C 1 month
Applications	Cancer-programmed cell death
Formula	C10H11N5O4
References	[1].G V Madhavan, et al. Synthesis and antiviral evaluation of 6'-substituted aristeromycins: potential mechanism-based inhibitors of S-adenosylhomocysteine hydrolase. J Med Chem \| [2].B Bostrom, et al. Inhibitory effect of adenosine dialdehyde on in situ murine neuroblastoma growth.Cancer Res. 1988 Nov 1; 48(21):5933-6. \| [3].V Ramakrishnan, et al. Adenosine dialdehyde and neplanocin A: Potent inhibitors of S-adenosylhomocysteine hydrolase in neuroblastoma N2a cells. Neurochem Int. 1987; 10(4):423-31.
MolecularWeight	265.23
Research Area	Cancer
Solubility	DMSO : 10 mg/mL (37.70 mM; Need ultrasonic)
Target	Nucleoside Antimetabolite/Analog
Pathway	Cell Cycle/DNA Damage

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Amount: 5mg

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Delivery expected until 4/13/2023

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