TBT1

Manufacturer	MedChem Express
Category	Inhibitors
Type	Inhibitors
Specific against	other
Amount	10mg
Item no.	HY-124789-10mg
CASRN	52535-76-9
Available
Product Description	TBT1 is a first-generation inhibitor of the MsbA transporter. TBT1 is an LPS transport inhibitor and MsbA ATPase stimulator in strains from the Acinetobacter genus. TBT1 stimulated ATPase activity with an EC50 of 13 µM.
StorageTemperature	Please store the product under the recommended conditions in the Certificate of Analysis.
Applications	COVID-19-immunoregulation
Formula	C16H14ClNO3S
References	[1].François A Thélot, et al. Distinct allosteric mechanisms of first-generation MsbA inhibitors. Science. 2021 Oct 29; 374(6567):580-585.
MolecularWeight	335.81
Research Area	Infection
Solubility	DMSO : 125 mg/mL (372.23 mM; ultrasonic and warming and heat to 60°C)
Target	Bacterial; Antibiotic
Pathway	Anti-infection

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Amount: 10mg

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Delivery expected until 4/6/2023

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