TBT1

Item no.	HY-124789-50mg
Manufacturer	MedChem Express
CASRN	52535-76-9
Amount	50 mg
Quantity options	100 mg 10 mM/1 mL 10 mg 1 ea 25 mg 50 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	99.55
Formula	C16H14ClNO3S
Citations	[1]François A Thélot, et al. Distinct allosteric mechanisms of first-generation MsbA inhibitors. Science. 2021 Oct 29;374(6567):580-585.
Smiles	O=C(C1=C(NC(C2=CC=C(Cl)C=C2)=O)SC3=C1CCCC3)O
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Shipping condition	Cool pack
Available
Manufacturer - Type	Reference compound
Manufacturer - Applications	COVID-19-immunoregulation
Manufacturer - Targets	Antibiotic; Bacterial
Shipping Temperature	Blue Ice
Storage Conditions	-20°C, 3 years (Powder)
Molecular Weight	335.81
Product Description	TBT1 is a first-generation inhibitor of the MsbA transporter. TBT1 is an LPS transport inhibitor and MsbA ATPase stimulator in strains from the Acinetobacter genus. TBT1 stimulated ATPase activity with an EC50 of 13 µM[1].
Manufacturer - Research Area	Infection
Solubility	DMSO : 125 mg/mL (ultrasonic; warming; heat to 60°C)
Manufacturer - Pathway	Anti-infection
Clinical information	No Development Reported

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HY-124789-50mg-safety-datasheet.pdf