Comparison

Syk-IN-4 European Partner

Item no. HY-131341-50mg
Manufacturer MedChem Express
CASRN 2932264-95-2
Amount 50 mg
Quantity options 100 mg 10mM/1mL 10 mg 1 mg 25 mg 50 mg 5 mg
Category
Type Inhibitors
Specific against other
Purity 98.0
Formula C21H25N9O
Citations [1]Neil P Grimster, et al. Optimization of a Series of Potent, Selective and Orally Bioavailable SYK Inhibitors. Bioorg Med Chem Lett. 2020 Jul 24;127433.
Smiles CC1=NN(C=C1CN(C)C)C2=NC(NC3=CC=C(N(C)N=C4C(NC)=O)C4=C3)=NC=C2
ECLASS 10.1 32160490
ECLASS 11.0 32160490
UNSPSC 12000000
Available
Product Description
Syk-IN-4 is a potent, selective and orally bioavailable SYK inhibitor with an IC50 of 0.31 nM. SYK has emerged as a potential target for autoimmunity and hematological cancers[1].
StorageTemperature
-20°C, 3 years; 4°C, 2 years (Powder)
Shipping
Room Temperature
Manufacturers Applications
COVID-19-immunoregulation
MolecularWeight
419.48
Clinical Information
No Development Reported
Manufacturers Research Area
Cancer; Inflammation/Immunology
Solubility
DMSO : 62.5 mg/mL (ultrasonic)
Target
Syk
Manufacturers Target
Syk
Manufacturers Pathway
Protein Tyrosine Kinase/RTK
Manufacturers Product type
Reference compound

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 50 mg
Available: In stock
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