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Targaprimir-96 (TFA)

Targaprimir-96 (TFA)

Item no.	HY-135276A-1ea
Manufacturer	MedChem Express
Amount	1 ea
Quantity options	100 mg 1 ea
Category	Inhibitors & Compound Libraries Small Molecules
Type	Molecules
Specific against	other
Citations	[1]Velagapudi SP, et al. Design of a small molecule against an oncogenic noncoding RNA. Proc Natl Acad Sci U S A. 2016 May 24;113(21):5898-903.
Smiles	OC(C(F)(F)F)=O.O=C(N)CN(C(CN(C(CN(C(CCCOC1=CC=CC(C2=NC3=CC=C(C4=NC5=CC=C(N6CCN(C)CC6)C=C5N4)C=C3N2)=C1)=O)CCC)=O)CCC)=O)CC7=CN(CCCNC(CCCOC8=C(C(C)(C)C)C=C(C9=NC%10=CC=C(N%11CCN(C)CC%11)C=C%10N9)C=C8C(C)(C)C)=O)N=N7
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Shipping Condition	Room temperature
Available
Manufacturer - Type	Reference compound
Manufacturer - Applications	Cancer-programmed cell death
Manufacturer - Targets	Apoptosis; MicroRNA
Shipping Temperature	Room temperature
Molecular Weight	1505.77
Product Description	Targaprimir-96 TFA is a potent inhibitor of microRNA-96 (miR-96) processing. Targaprimir-96 TFA selectively modulates miR-96 production in cancer cells and triggers apoptosis. Targaprimir-96 TFA binds primary miR-96 (pri-miR-96) with low nanomolar affinity. Targaprimir-96 TFA directly engages pri-miR-96 in breast cancer cells and is ineffective on healthy breast cells[1].
Manufacturer - Research Area	Cancer
Solubility	10 mM in DMSO
Manufacturer - Pathway	Apoptosis; Epigenetics
Clinical information	No Development Reported

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