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SB1-G-187

SB1-G-187

Item no.	HY-137342-50mg
Manufacturer	MedChem Express
CASRN	2769753-18-4
Amount	50 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	98.01
Formula	C52H54F3N9O10
Citations	[1]Katherine A Donovan, et al. Mapping the Degradable Kinome Provides a Resource for Expedited Degrader Development. Cell. 2020 Dec 10;183(6):1714-1731.e10.
Smiles	O=C1N(C2CCC(NC2=O)=O)C(C3=C1C=CC=C3OCC(NCCOCCOCCOCCCN4CCN(CC5=C(C(F)(F)F)C=C(NC(C6=CC(C#CC7=CN=C8N7N=CC=C8)=C(C)C=C6)=O)C=C5)CC4)=O)=O
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Product Description	SB1-G-187, a PROTAC, is a multi-kinase degrader[1]. SB1-G-187 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
StorageTemperature	-20°C (Powder, stored under nitrogen)
Shipping	Blue Ice
Manufacturers Applications	Cancer-Kinase/protease
MolecularWeight	1022.03
Clinical_Information	No Development Reported
Manufacturers Research_Area	Cancer
Solubility	DMSO : 100 mg/mL (ultrasonic)
Manufacturers Target	PROTACs
Pathway	PROTAC
Manufacturers Product type	Reference compound

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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