SAE-14

Manufacturer	MedChem Express
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Amount	10 mg
Item no.	HY-147222-10mg
CASRN	1241280-25-0
eClass 6.1	30220300
eClass 9.0	32160605
Available
Product Description	SAE-14 (compound SAE-14) is a potent, specific GPR183 antagonist with an IC50 value of 28.5 nM, can antagonize 7α, 25-OHC–induced calcium mobilization with IC50 value below 50 nM in HL-60 cells. GPR183 antagonist-1 can reverse allodynia in mice[1].
StorageTemperature	-20°C, 3 years (Powder)
Shipping	Blue Ice
Manufacturers Applications	COVID-19-immunoregulation
MolecularWeight	364.36
Clinical_Information	No Development Reported
Manufacturers Research_Area	Inflammation/Immunology; Neurological Disease
Solubility	DMSO : 100 mg/mL (ultrasonic; warming; heat to 60°C)
Manufacturers Target	EBI2/GPR183
Pathway	GPCR/G Protein
Manufacturers Product type	Reference compound

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