Comparison

Auristatin E European Partner

Item no. HY-15582-500mg
Manufacturer MedChem Express
CASRN 160800-57-7
Amount 500 mg
Quantity options 100 mg 10 mMx1 mL 10 mg 1 mg 250 mg 500 mg 50 mg 5 mg
Category
Type Inhibitors
Specific against other
Purity 99.89
Formula C40H69N5O7
Citations [1]MADDON Paul J, et al. PSMA ANTIBODIES AND PROTEIN MULTIMER. 2002 October 23. WO 03/034903 A2
[2]Peter D. Senter, et al. PENTAPEPTIDE COMPOUNDS AND USES RELATED THERETO. 2005 Jan. 13. US 2005/0009751 A l.
[3]LAW, Che-Leung, et al. TREATMENT OF IMMUNOLOGICAL DISORDERS 5 USING ANTI-CD30 ANTIBODIES. 2002 November 20. WO 03/043583 A2.
Smiles CC(C)[C@H](N(C)C)C(N[C@H](C(N([C@@H]([C@@H](C)CC)[C@@H](CC(N1CCC[C@@]1([H])[C@H](OC)[C@@H](C)C(N[C@H](C)[C@H](C2=CC=CC=C2)O)=O)=O)OC)C)=O)C(C)C)=O
ECLASS 10.1 32160490
ECLASS 11.0 32160490
UNSPSC 12000000
Shipping condition Room temperature
Available
Manufacturer - Type
ADC Related
Manufacturer - Applications
Cancer-programmed cell death
Manufacturer - Targets
ADC Cytotoxin; Microtubule/Tubulin
Shipping Temperature
Room Temperature
Storage Conditions
4°C (Powder, protect from light, stored under nitrogen)
Molecular Weight
732.01
Product Description
Auristatin E is a cytotoxic microtubule polymerization inhibitor with potent and selective antitumor activity. Auristatin E is a cytotoxin in antibody-drug conjugates (ADC). Auristatin E inhibits cell division by blocking the polymerisation of tubulin, promising for research in B-cell malignancies. Auristatin E, a synthetic analogue of the Dolastatin 10 (HY-15580), is linear peptides comprised of four amino acids[1][2][3].
Manufacturer - Research Area
Cancer
Solubility
DMSO : 100 mg/mL (ultrasonic)
Manufacturer - Pathway
Antibody-drug Conjugate/ADC Related; Cell Cycle/DNA Damage; Cytoskeleton
Isoform
Auristatin
Clinical information
No Development Reported

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 500 mg
Available: In stock
available

Compare

Add to wishlist

Get an offer

Request delivery time

Ask a technical question

Submit a bulk request

Questions about this Product?
 
Close