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Proxyphylline

Proxyphylline

Item no.	HY-B1742-500mg
Manufacturer	MedChem Express
CASRN	603-00-9
Amount	500 mg
Quantity options	100 mg 10 mM/1 mL 500 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	99.93
Citations	[1]Takeda K, et al. Effects of aminophylline, proxyphylline and a proxyphylline-Melilotus extract-rutin mixture(theoesberiven) on the heart and the coronary circulation. Jpn J Pharmacol. 1977 Oct;27(5):709-20.\|[2]Kukovetz WR, et al. Overadditive synergism between theophylline, diprophylline and proxyphylline in tracheal smooth muscle relaxation. Arzneimittelforschung. 1983;33(10):1450-4.\|[3]Rasmussen FV, et al. Pharmacokinetics and bronchodilatory effect of proxyphylline and theophylline. Eur J Respir Dis. 1984 Jan;65(1):20-7.\|[4]Selvig K, et al. Inhibition of human lung cyclic nucleotide phosphodiesterases by proxyphylline, theophylline and their metabolites. Acta Pharmacol Toxicol (Copenh). 1982 Sep;51(3):250-2.
Smiles	O=C(N1C)N(C)C2=C(N(CC(O)C)C=N2)C1=O
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	603-00-9
Similar products	603-00-9
Shipping Condition	Room temperature
Available
Manufacturer - Type	Natural Products
Manufacturer - Applications	COVID-19-immunoregulation
Manufacturer - Targets	Adenosine Receptor; Phosphodiesterase (PDE)
Shipping Temperature	Room Temperature
Storage Conditions	-20°C, 3 years; 4°C, 2 years (Powder)
Molecular Weight	238.25
Product Description	Proxyphylline is a methylxanthine derivative used as a cardiac stimulant, vasodilator and bronchodilator[1].
Manufacturer - Research Area	Cardiovascular Disease
Solubility	DMSO: ≥ 100 mg/mL
Manufacturer - Pathway	GPCR/G Protein; Metabolic Enzyme/Protease
Clinical information	Launched

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HY-B1742-500mg-safety-datasheet.pdf