Comparison

trans-Isoferulic acid European Partner

Item no. HY-N0761A-250mg
Manufacturer MedChem Express
CASRN 25522-33-2
Amount 250 mg
Quantity options 100 mg 10 mM/1 mL 1 ea 250 mg
Category
Type Inhibitors
Specific against other
Purity 99.89
Citations [1]Kai-Hui Sun, et al. A new indole-type alkaloid from the roots of <i>Clematis florida var. plena</i>. Nat Prod Res. 2019 Oct;33(20):2925-2931.|[2]Matharage Gayani Dilshara, et al. Downregulation of NO and PGE2 in LPS-stimulated BV2 microglial cells by trans-isoferulic acid via suppression of PI3K/Akt-dependent NF-κB and activation of Nrf2-mediated HO-1. Int Immunopharmacol. 2014 Jan;18(1):203-11.
Smiles O=C(O)/C=C/C1=CC=C(OC)C(O)=C1
ECLASS 10.1 32160490
ECLASS 11.0 32160490
UNSPSC 12000000
Alias trans-3-Hydroxy-4-methoxycinnamic acid
Shipping Condition Room temperature
Available
Manufacturer - Type
Natural Products
Manufacturer - Applications
COVID-19-immunoregulation
Manufacturer - Targets
NO Synthase; Prostaglandin Receptor
Shipping Temperature
Room Temperature
Storage Conditions
4°C (Powder, stored under nitrogen)
Molecular Weight
194.19
Product Description
trans-Isoferulic acid (trans-3-Hydroxy-4-methoxycinnamic acid) is an aromatic acid isolated from the roots of Clematis florida var. plena. trans-Isoferulic acid exhibits anti-inflammatory activity[1].trans-isoferulic acid suppresses NO and PGE2 production through the induction of Nrf2-dependent heme oxygenase-1 (HO-1)[2].
Manufacturer - Research Area
Inflammation/Immunology
Solubility
DMSO: 100 mg/mL (ultrasonic)
Manufacturer - Pathway
GPCR/G Protein; Immunology/Inflammation
Isoform
EP; Human Endogenous Metabolite
Clinical information
No Development Reported

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 250 mg
Available: In stock
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