Comparison

Vanoxerine European Partner

Item no. HY-13217A-10mg
Manufacturer MedChem Express
CASRN 67469-69-6
Amount 10 mg
Quantity options 100 mg 10 mg 1 ea 50 mg
Category
Type Inhibitors
Specific against other
Citations Biochem Biophys Res Commun. 2020 May 14;525(4):989-996.
Front Cell Neurosci. 2018 Sep 11;12:309.
Neuron. 2023 Mar 6;S0896-6273(23)00121-6.
bioRxiv. 2024 Dec 23:2024.12.22.629999.
Nature. 2024 Aug;632(8025):686-694.
University of Groningen. 2016 Jun 1.
[1]Rothman RB, et al. Dopamine transport inhibitors based on GBR12909 and benztropine as potential medications to treat cocaine addiction. Biochem Pharmacol. 2008 Jan 1;75(1):2-16.
[2]Andersen PH. The dopamine inhibitor GBR 12909: selectivity and molecular mechanism of action. Eur J Pharmacol.
[3]Hirate K, et al. Characteristics of the ambulation-increasing effect of GBR-12909, a selective dopamine uptakeinhibitor, in mice. Jpn J Pharmacol. 1991 Apr;55(4):501-11.
Smiles FC1=CC=C(C(C2=CC=C(F)C=C2)OCCN3CCN(CCCC4=CC=CC=C4)CC3)C=C1
ECLASS 10.1 32160490
ECLASS 11.0 32160490
UNSPSC 12000000
Alias GBR 12909,I893
Shipping Condition Room temperature
Available
Manufacturer - Type
Reference compound
Manufacturer - Applications
Neuroscience-Neuromodulation
Manufacturer - Targets
Dopamine Transporter
Shipping Temperature
Room temperature
Molecular Weight
450.56
Product Description
Vanoxerine (GBR-12909) is a competitive, potent, and highly selective dopamine reuptake inhibitor (Ki=1 nM). Vanoxerine (GBR-12909) binds to the target site on the dopamine transporter (DAT)[1].
Manufacturer - Research Area
Neurological Disease
Solubility
10 mM in DMSO
Manufacturer - Pathway
Neuronal Signaling
Clinical information
Phase 3

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 10 mg
Available: In stock
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