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Erlotinib hydrochloride

Erlotinib hydrochloride

Item no.	TMO-T0373L-500mg
Manufacturer	TargetMol
CASRN	183319-69-9
Amount	500 mg
Quantity options	100 mg 1 mL x 10 mM (in DMSO) 10 mg 1 g 1 mL 200 mg 500 mg 50 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	99.79%
Citations	Wada Y, et al. Epidermal growth factor receptor inhibition with erlotinib partially prevents cisplatin-induced nephrotoxicity in rats. PLoS One. 2014 Nov 12;9(11):e111728.
Smiles	Cl.COCCOC1=C(OCCOC)C=C2C(NC3=CC(=CC=C3)C#C)=NC=NC2=C1
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	OSI-744,NSC 718781,Erlotinib HCl,CP-358774
Shipping Condition	Cool pack
Available
Manufacturer - Targets	Autophagy\|\|\|EGFR
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	429.9
Description	Erlotinib hydrochloride (NSC 718781) is an EGFR inhibitor (IC50: 2 nM). It is used for the treatment of non-small cell lung cancer.
Pathways	Autophagy\|\|\|Angiogenesis\|\|\|JAK/STAT signaling\|\|\|Tyrosine Kinase/Adaptors

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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