Comparison

Erlotinib hydrochloride European Partner

Item no. TMO-T0373L-200mg
Manufacturer TargetMol
CASRN 183319-69-9
Amount 200 mg
Quantity options 100 mg 1 mL x 10 mM (in DMSO) 10 mg 1 g 1 mL 200 mg 500 mg 50 mg
Category
Type Molecules
Specific against other
Purity 0,9952
Citations 1. Moyer JD, et al. Y Res. 1997, 57(21), 4838-4848.
Smiles Cl.COCCOC1=C(OCCOC)C=C2C(NC3=CC(=CC=C3)C#C)=NC=NC2=C1
ECLASS 10.1 32169090
ECLASS 11.0 32169090
UNSPSC 12000000
Alias OSI-744,NSC 718781,Erlotinib HCl,CP-358774
Shipping Condition Cool pack
Available
Manufacturer - Targets
Autophagy|||EGFR
Shipping Temperature
Cool pack
Storage Conditions
-20
Molecular Weight
429.9
Description
Erlotinib hydrochloride (NSC 718781) is an EGFR inhibitor (IC50: 2 nM). It is used for the treatment of non-small cell lung cancer.
Pathways
Autophagy|||Angiogenesis|||JAK/STAT signaling|||Tyrosine Kinase/Adaptors
Bioactivity
Erlotinib is a direct acting inhibitor against human EGFR tyrosine kinase (IC50: 2 nM). Erlotinib hydrochloride (trade name Tarceva) is a drug used in the treatment of pancreatic Y, non-small cell lung Y and some other types of Y.
Receptor
EGFR/HER1

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 200 mg
Available: In stock
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