« Back
Home /
JNJ-10198409

JNJ-10198409

Item no.	TMO-T15616-10mg
Manufacturer	TargetMol
CASRN	627518-40-5
Amount	10 mg
Quantity options	100 mg 1 mL x 10 mM (in DMSO) 10 mg 1 mg 1 mL 200 mg 25 mg 50 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	98.51%
Citations	Ho CY, et al. (6,7-Dimethoxy-2,4-dihydroindeno[1,2-c]pyrazol-3-yl)phenylamines: platelet-derived growth factor receptor tyrosine kinase inhibitors with broad antiproliferative activity against tumor cells. J Med Chem. 2005 Dec 29;48(26):8163-73.
Smiles	COc1cc2Cc3c(Nc4cccc(F)c4)n[nH]c3-c2cc1OC
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	JNJ-10198409
Shipping Condition	Cool pack
Available
Manufacturer - Targets	PDGFR
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	325.34
Description	JNJ- 10198409 is a relatively selective and ATP competitive PDGF-RTK inhibitor (IC50=2 nM). JNJ-10198409 has good activity against PDGFR-β kinase (IC50=4.2 nM) and PDGFR-α kinase (IC50=45 nM). It is a dual-mechanism, antiangiogenic, and tumor cell antiproliferative agent.
Pathways	Angiogenesis\|\|\|Tyrosine Kinase/Adaptors

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

TMO-T15616-10mg-datasheet.pdf

Request safety datasheet

Simple Order Order Subscription

Amount: 10 mg

available

Compare

Add to wishlist

Get an offer

Request delivery time

Ask a technical question