Comparison

JNJ-10198409 European Partner

Item no. TMO-T15616-200mg
Manufacturer TargetMol
CASRN 627518-40-5
Amount 200 mg
Quantity options 100 mg 1 mL x 10 mM (in DMSO) 10 mg 1 mg 1 mL 200 mg 25 mg 50 mg 5 mg
Category
Type Molecules
Specific against other
Smiles COc1cc2Cc3c(Nc4cccc(F)c4)n[nH]c3-c2cc1OC
ECLASS 10.1 32169090
ECLASS 11.0 32169090
UNSPSC 12000000
Alias JNJ-​10198409
Shipping Condition Cool pack
Available
Manufacturer - Targets
PDGFR
Shipping Temperature
Cool pack
Storage Conditions
-20
Molecular Weight
325.34
Description
JNJ- 10198409 is a relatively selective and ATP competitive PDGF-RTK inhibitor (IC50=2 nM). JNJ-10198409 has good activity against PDGFR-β kinase (IC50=4.2 nM) and PDGFR-α kinase (IC50=45 nM). It is a dual-mechanism, antiangiogenic, and tumor cell antiproliferative agent.
Pathways
Angiogenesis|||Tyrosine Kinase/Adaptors

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 200 mg
Available: In stock
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