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Methoxyamine HCl

Methoxyamine HCl

Item no.	TMO-T21320-5mg
Manufacturer	TargetMol
CASRN	593-56-6
Amount	5 mg
Quantity options	1000 mg 100 mg 1 g 1 mL 5 g 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Citations	Yan T, Seo Y, Schupp JE, Zeng X, Desai AB, Kinsella TJ. Methoxyamine potentiates iododeoxyuridine-induced radiosensitization by altering cell cycle kinetics and enhancing senescence. Mol Cancer Ther. 2006 Apr;5(4):893-902. PubMed PMID: 16648559.
Smiles	Cl.CON
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	TRC-102, TRC 102, Methoxyamine, TRC102
Shipping condition	Cool pack
Available
Shipping Temperature	cool pack
Storage Conditions	-20°
Molecular Weight	83, 51
Description	Methoxyamine HCl (Methoxyamine) covalently binds to apurinic/apyrimidinic (AP) DNA damage sites and inhibits base excision repair (BER), which may result in an increase in DNA strand breaks and apoptosis. Methoxyamine is an orally bioavailable small molecule inhibitor with potential adjuvant activity. This agent may potentiate the anti-tumor activity of alkylating agents.
Bioactivity	Methoxyamine HCl covalently binds to apurinic/apyrimidinic (AP) DNA damage sites and inhibits base excision repair (BER), which may result in an increase in DNA strand breaks and apoptosis. Methoxyamine is an orally bioavailable small molecule inhibitor with potential adjuvant activity. This agent may potentiate the anti-tumor activity of alkylating agents.
Pathways	Others

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Amount: 5 mg

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