Comparison

Sulfatinib European Partner

Item no. TMO-T4075-200mg
Manufacturer TargetMol
CASRN 1308672-74-3
Amount 200 mg
Quantity options 100 mg 1 mL x 10 mM (in DMSO) 10 mg 1 mg 1 mL 200 mg 25 mg 2 mg 500 mg 50 mg 5 mg
Category
Type Inhibitors
Specific against other
Purity 0,9992
Formula C24H28N6O3S
Smiles CN(C)CCNS(=O)(=O)Cc1cccc(Nc2nccc(Oc3ccc4[nH]c(C)cc4c3)n2)c1
ECLASS 10.1 32160490
ECLASS 11.0 32160490
UNSPSC 12000000
Alias KDR-IN-1
Shipping Condition Cool pack
Available
Manufacturer - Targets
VEGFR|||FGFR|||Potassium Channel
Shipping Temperature
Cool pack
Storage Conditions
-20
Molecular Weight
480.58
Description
Sulfatinib (KDR-IN-1) (HMPL-012) is a potent and highly selective tyrosine kinase inhibitor against VEGFR1/2/3, FGFR1 and CSF1R with IC 50 s ranging from 1 to 24 nM.
Pathways
Membrane transporter/Ion channel|||Angiogenesis|||Tyrosine Kinase/Adaptors
Bioactivity
Sulfatinib may be a potent drug for cancer. It inhibits KDR and FGFR1 enzymatic activity. It also is a hERG inhibitor.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 200 mg
Available: In stock
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