Mebiol Gel

Note:

This product is packaged with RP Drying Agent packs to absorb moisture, oxygen and corrosive gases. It is therefore subject to European Commerce Area Import Regulation (EC) No. 1272/2008 - Classification, Labeling, and Packaging of Substances and Mixtures (CLP). Applies to EEA (i.e. EU27 countries, Iceland, Liechtenstein, Norway, UK).

For additional information, see the following:
OSHA Europe
RP Agent Manufactuer' s Statement

Introduction to Mebiol® Gel

Hydrogels are a diverse class of polymeric materials characterized by their network-like structure and high water content. Hydrogels of many kinds have found a wide variety of applications in medicine and life science research weighted towards, but not at all limited to three-dimensional cell culture, tissue engineering, and drug delivery. Properties highly favorable to cell culture and tissue engineering applications prompted the commercialization of Mebiol® Gel, a copolymer of poly(N-isopropylacrylamide) and poly(ethylene glycol) (PNIPAAm-PEG) for research purposes in the early 2000' s.

Mebiol® Gel' s defining feature, in contrast to other commercially available hydrogels, is its temperature reversible sol-gel transition. When cooled, Mebiol® Gel is a sol (handles like a liquid) but becomes a rigid hydrogel at higher temperatures. In practice, this means extremely easy cell handling. Cultures are seeded into cooled Mebiol® Gel and recovered conveniently by cooling the culture vessel and centrifugation. In the gel state, the highly lipophylic environment of the Mebiol® Gel presents an efficient niche for cell proliferation, cell communication, gas and mass exchange, and protection of cells and tissue from shear forces.

Features

· Easy handling
· Non-toxic, biocompatible
· 100% synthetic, pathogen free
· High transparency for cell observation
· Proven performance.

Preparation

Application

· Stem cell and pluripotent stem cell culture, expansion, and differentiation
· Spheroid culture
· Cell implantation
· Organ and Tissue Regeneration
· Drug Delivery
· Non-cell culture application

Application Examples