4-IBP

Item no.	HY-100155-10mM
Manufacturer	MedChem Express
CASRN	155798-08-6
Amount	10mM/1mL
Quantity options	100 mg 10mM/1mL 10 mg 50 mg 5 mg
Category	Oncology Inhibitors & Compound Libraries Small Molecules By Organ Lung Cancer Brain Cancer
Type	Inhibitors
Specific against	other
Purity	99.81
Formula	C19H21IN2O
Citations	[1]Mégalizzi V, et al. 4-IBP, a sigma1 receptor agonist, decreases the migration of human cancer cells, including glioblastoma cells, in vitro and sensitizes them in vitro and in vivo to cytotoxic insults of proapoptotic and proautophagic drugs. Neoplasia. 2007 May;9(5):358-69.
Smiles	O=C(NC1CCN(CC2=CC=CC=C2)CC1)C3=CC=C(I)C=C3
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	155798-08-6
Available
Product Description	4-IBP is a selective σ1 agonist, binding to σ1 receptors with high affinity (Ki = 1.7 nM) and with slightly weaker affinity to σ2 receptors (Ki = 25.2 nM).
StorageTemperature	-20°C, 3 years; 4°C, 2 years (Powder)
Shipping	Room Temperature
Manufacturers Applications	Cancer-programmed cell death
MolecularWeight	420.29
Clinical_Information	No Development Reported
Manufacturers Research Area	Cancer
Solubility	DMSO : 100 mg/mL (ultrasonic)
Manufacturers Target	Sigma Receptor
Isoform	Sigma 1 Receptor; Sigma 2 Receptor
Pathway	Neuronal Signaling

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Amount: 10mM/1mL

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