PTACH

Manufacturer	MedChem Express
Category	Oncology Inhibitors & Compound Libraries Small Molecules By Organ Lung Cancer Colorectal Cancer Breast Cancer
Type	Inhibitors
Specific against	other
Amount	10mM/1mL
Item no.	HY-12954-10mM
Targets	HDAC; HIV
CASRN	848354-66-5
eClass 6.1	30220300
eClass 9.0	32160605
Available
Product Description	PTACH (NCH-51) is a potent HDAC inhibitor with IC50s of 48 nM, 32 nM, and 41 nM for HDAC1, HDAC4, and HDAC6, respectively. PTACH exerts potent growth inhibition against various cancer cells (EC50s of 1.1-9.1 µM) [1][2].
StorageTemperature	-20°C, 3 years; 4°C, 2 years (Powder)
Shipping	Room Temperature
Manufacturers Applications	Cancer-programmed cell death
MolecularWeight	390.56
Clinical_Information	No Development Reported
Manufacturers Research_Area	Cancer; Infection
Solubility	DMSO : 50 mg/mL (ultrasonic)
Manufacturers Target	HDAC; HIV
Isoform	HDAC1; HDAC4; HDAC6; HIV-1
Pathway	Anti-infection; Cell Cycle/DNA Damage; Epigenetics
Manufacturers Product type	Reference compound

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HY-12954-10mM-safety-datasheet.pdf