« Back
Home /
Eliglustat

Eliglustat

Item no.	HY-14885-10mg
Manufacturer	MedChem Express
CASRN	491833-29-5
Amount	10 mg
Quantity options	100 mg 10 mM/1 mL 10 mg 1 mg 25 mg 50 mg 5 mg
Category	Oncology Metabolism Cholesterol & Lipid Metabolism Enzymes Other Fatty Acid Enzymes Inhibitors & Compound Libraries Small Molecules By Organ Lung Cancer
Type	Inhibitors
Specific against	other
Purity	99.95
Citations	[1]McEachern KA, et al. A specific and potent inhibitor of glucosylceramide synthase for substrate inhibition therapy ofGaucher disease. Mol Genet Metab. 2007 Jul;91(3):259-68. Cell Death Dis. 2021 Oct 6;12(10):911.\|EMBO J. 2022 Dec 12;e110553.\|Nat Commun. 2020 Aug 27;11(1):4279.\|Nat Commun. 2024 Aug 14;15(1):6970.\|bioRxiv. 2021 Feb 2.\|Cancer Discov. 2022 Nov 4;CD-22-0535.\|Immunity. 2021 Jan 12;54(1):132-150.e9.\|Int J Biol Macromol. 2024 Dec 2:285:138303.\|Leiden University. 2022 Jun 15.\|PLoS One. 2021 Oct 25;16(10):e0247211.\|Stem Cells Transl Med. 2021 Mar 3.
Smiles	CCCCCCCC(N[C@H](CN1CCCC1)[C@@H](C2=CC=C(OCCO3)C3=C2)O)=O
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	Genz 99067
Shipping Condition	Room temperature
Available
Manufacturer - Type	Reference compound
Manufacturer - Applications	Metabolism-protein/nucleotide metabolism
Manufacturer - Targets	Glucosylceramide Synthase (GCS)
Shipping Temperature	Room Temperature
Storage Conditions	-20°C, 3 years; 4°C, 2 years (Powder)
Molecular Weight	404.54
Product Description	Eliglustat is an specific, potent and orally active glucocerebroside synthase inhibitor with an IC50 of 24 nM.
Manufacturer - Research Area	Metabolic Disease; Cancer
Solubility	DMSO: 100 mg/mL (ultrasonic)
Manufacturer - Pathway	Neuronal Signaling
Clinical information	Launched

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

Request product datasheet

HY-14885-10mg-safety-datasheet.pdf