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UNBS5162

UNBS5162

Item no.	HY-16509-10mM
Manufacturer	MedChem Express
CASRN	956590-23-1
Amount	10 mM/1 mL
Quantity options	100 mg 10 mM/1 mL 10 mg 25 mg 50 mg 5 mg
Category	Oncology Inhibitors & Compound Libraries Small Molecules By Organ Testicular & Prostate Cancer
Type	Inhibitors
Specific against	other
Purity	99.92
Citations	[1]Mijatovic T, et al. UNBS5162, a novel naphthalimide that decreases CXCL chemokine expression in experimental prostate cancers. Neoplasia. 2008 Jun;10(6):573-86.\|[2]Tina Mahieu, et al. UNBS5162: A novel naphthalimide derivative with potent pro-autophagic effects in human cancer cells. Cancer Research, 2007 May; 67(9) Supplement.\|[3]He D, et al. UNBS5162 inhibits the proliferation of esophageal cancer squamous cells via the PI3K/AKT signaling pathway. Mol Med Rep. 2018 Jan;17(1):549-555.
Smiles	O=C(N)NC1=CC2=CC=CC(C(N(CCN(C)C)C3=O)=O)=C2C3=C1
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	956590-23-1
Shipping Condition	Room temperature
Available
Manufacturer - Type	Reference compound
Manufacturer - Applications	Cancer-Kinase/protease
Manufacturer - Targets	Autophagy; CXCR
Shipping Temperature	Room Temperature
Storage Conditions	-20°C, 3 years; 4°C, 2 years (Powder)
Molecular Weight	326.35
Product Description	UNBS5162 is a pan-antagonist of CXCL chemokine expression, with anti-tumor activity.
Manufacturer - Research Area	Cancer; Endocrinology
Solubility	DMSO: 21.5 mg/mL (ultrasonic; warming)
Manufacturer - Pathway	Autophagy; GPCR/G Protein; Immunology/Inflammation
Isoform	CXCR
Clinical information	No Development Reported

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HY-16509-10mM-safety-datasheet.pdf