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Colistin (sulfate)

Colistin (sulfate)

Item no.	HY-A0089-500mg
Manufacturer	MedChem Express
CASRN	1264-72-8
Amount	500 mg
Quantity options	100 mg 10 mM/1 mL 1 g 500 mg 5 g
Category	Food Safety Antibiotics Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	98.0
Citations	[1]Hancock RE et al. Peptide antibiotics. Antimicrob Agents Chemother. 1999 Jun;43(6):1317-23.\|[2]Li J, et al. In vitro pharmacodynamic properties of colistin and colistin methanesulfonate againstPseudomonas aeruginosa isolates from patients with cystic fibrosis. Antimicrob Agents Chemother. 2001 Mar;45(3):781-5.\|[3]W S Yapa S, et al. Population pharmacokinetics of colistin methanesulfonate in rats: achieving sustained lung concentrations of colistin for targeting respiratory infections. Antimicrob Agents Chemother. 2013 Oct;57(10):5087-95.\|[4]Fleury MA, et al. Impact of two different colistin dosing strategies on healthy piglet fecal microbiota. Res Vet Sci. 2016 Aug;107:152-60. Adv Sci (Weinh). 2020 Jul 21;7(17):2001374. Anim Dis. 2021;1(1):26. Arthritis Res Ther. 2025 Jul 7;27(1):137. bioRxiv. 2025 January 19. bioRxiv. 2025 January 25. Cell Host Microbe. 2025 Jun 11;33(6):915-931.e9. Cell Mol Gastroenterol Hepatol. 2025 Feb 7:101474. Clin Microbiol Infect. 2020 Sep;26(9):1264-1265. Dev Cell. 2025 May 15:S1534-5807(25)00287-4. Hum Exp Toxicol. 2021 Oct;40(10):1767-1780. J Antibiot (Tokyo). 2019 Aug;72(8):600-604. J Antibiot (Tokyo). 2025 Mar;78(4):265-273. Nat Commun. 2022 Mar 2;13(1):1116. Nat Commun. 2024 Sep 10;15(1):7914. Patent. US20200101105A1. PLoS One. 2025 Jul 10;20(7):e0328167. Sci Rep. 2025 May 8;15(1):16114. Animal Diseases. 2024 Apr 3. Antimicrob Agents Chemother. 2025 Aug 6;69(8):e0037925. Cell Host Microbe. 2024 May 13:S1931-3128(24)00137-9. Dev Cell. 2025 May 15:S1534-5807(25)00287-4. Emerg Microbes Infect. 2024 Dec;13(1):2321981. Int Immunopharmacol. 2025 May 21:159:114888. Microorganisms. 2024 Mar 13;12(3):575. Vet Microbiol. 2024 May:292:110046.
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ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	Polymyxin E (sulfate)
Shipping Condition	Room temperature
Available
Manufacturer - Type	Natural Products
Manufacturer - Applications	COVID-19-immunoregulation
Manufacturer - Category	Reference compound / Active compounds; API; Natural Products
Manufacturer - Targets	Antibiotic; Autophagy; Bacterial
Manufacturer - HS Code	H301
Shipping Temperature	Room Temperature
Storage Conditions	4°C (Powder, sealed storage, away from moisture)
Molecular Weight	1400.64
Product Description	Colistin sulfate is a polypeptide antibiotic which inhibits gram-negative bacteria by binding to lipopolysaccharides and phospholipids in the outer cell membrane of gram-negative bacteria.
Manufacturer - Research Area	Infection
Solubility	DMSO : < 1 mg/mL (ultrasonic; warming; heat to 60°C)\|H2O : 50 mg/mL (ultrasonic)
Manufacturer - Pathway	Anti-infection; Autophagy
Clinical information	Launched
UNSPSC Code	12352211
Precautionary	H301

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

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