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Donepezil (Hydrochloride)

Donepezil (Hydrochloride)

Manufacturer	MedChem Express
Category	Oncology Neuroscience Molecular Targets for Neuroscience Aging & Neurological Disorders Inhibitors & Compound Libraries Small Molecules By Organ Brain Cancer
Type	Inhibitors
Specific against	other
Clone	N/A
Amount	10mM/1mL
Item no.	HY-B0034-10mM
Targets	AChE
CASRN	120011-70-3
eClass 6.1	30220300
eClass 9.0	32160605
Available
Product Description	Donepezil Hydrochloride (E2020) is a reversible, selective AChE inhibitor with an IC50 of 6.7 nM for AChE activity. Donepezil shows high selectivity for AChE over BuChE[1]. Donepezil exhibits neuroprotective effect on Aβ42 neurotoxicity[2].
StorageTemperature	4°C (Powder, sealed storage, away from moisture)
Shipping	Room Temperature
Manufacturers Applications	Neuroscience-Neurodegeneration
MolecularWeight	415.95
Clinical_Information	Launched
Manufacturers Research_Area	Neurological Disease; Cancer
Solubility	DMSO : 6.2 mg/mL (warming)\|H2O : 25 mg/mL (ultrasonic)
Manufacturers Target	Cholinesterase (ChE)
Isoform	AChE
Pathway	Neuronal Signaling
Manufacturers Product type	Reference compound

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HY-B0034-10mM-safety-datasheet.pdf