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Sulfamethoxazole

Sulfamethoxazole

Item no.	HY-B0322-100mg
Manufacturer	MedChem Express
CASRN	723-46-6
Amount	100 mg
Quantity options	100 mg 10 mM/1 mL 500 mg
Category	Food Safety Antibiotics Vitamines Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	99.91
Citations	[1]Zambuzzi-Carvalho et al. Transcriptional profile of the human pathogenic fungus Paracoccidioides lutzii in response to sulfamethoxazole. Med Mycol. 2015;53(5):477-492. \|[2]Choonara BF, et al. A menthol-based solid dispersion technique for enhanced solubility and dissolution of sulfamethoxazole from an oral tablet matrix. AAPS PharmSciTech. 2015 Aug;16(4):771-86.\|[3]Ogata H, et al. Dose Dependent Effect of Sulfamethoxazole on Inhibiting KATP Channel of Mouse Pancreatic β Cell. Dose Response. 2023 Sep 28;21(3):15593258231203611. Autophagy. 2023 Jun 13;1-17.\|Bioresour Technol Rep. 2023 Dec, 24, 101619.\|bioRxiv. 2024 May 10.\|bioRxiv. 2025 January 19.\|Chemosphere. 2019 Jun;225:378-387. \|Clin Chem. 2019 Dec;65(12):1522-1531. \|Ecotoxicol Environ Saf. 2023 Mar 1;253:114711.\|Signal Transduct Target Ther. 2023 Sep 18;8(1):353.\|Water Res. 2023 May 21, 120110.\|Nat Commun. 2022 Mar 2;13(1):1116.
Smiles	O=S(C1=CC=C(N)C=C1)(NC2=NOC(C)=C2)=O
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	Ro 4-2130
Shipping Condition	Room temperature
Available
Manufacturer - Type	Reference compound
Manufacturer - Applications	COVID-19-immunoregulation
Manufacturer - Targets	Antibiotic; Bacterial
Shipping Temperature	Room Temperature
Storage Conditions	-20°C, 3 years; 4°C, 2 years (Powder)
Molecular Weight	253.28
Product Description	Sulfamethoxazole (Ro 4-2130) is a sulfonamide antibiotic with a widespread antibacterial activity. Sulfamethoxazole inhibits bacterial folate metabolism by competing with 4-Aminobenzoic acid (HY-B1008) (PABA) to act on dihydropteroate synthetase and dihydropteroate reductase. Sulfamethoxazole can be used for the study of urinary tract infections (UTIs), prostatitis, and bronchitis[1][2][3].
Manufacturer - Research Area	Infection; Cancer
Solubility	DMSO: ≥ 100 mg/mL\|H2O: < 0.1 mg/mL
Manufacturer - Pathway	Anti-infection
Clinical information	Launched

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HY-B0322-100mg-safety-datasheet.pdf