« Back
Home /
Ciprofloxacin

Ciprofloxacin

Item no.	HY-B0356-1g
Manufacturer	MedChem Express
CASRN	85721-33-1
Amount	1 g
Quantity options	1 g 500 mg 5 g
Category	Food Safety Antibiotics Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	99.94
Citations	[1]Tsai WC, et, al. Ciprofloxacin-mediated cell proliferation inhibition and G2/M cell cycle arrest in rat tendon cells. Arthritis Rheum. 2008 Jun;58(6):1657-63.\|[2]Steenbergen J, et, al. In Vitro and In Vivo Activity of Omadacycline against Two Biothreat Pathogens, Bacillus anthracis and Yersinia pestis. Antimicrob Agents Chemother. 2017 Apr 24;61(5):e02434-16.\|[3]Hamblin KA, et, al. Inhaled Liposomal Ciprofloxacin Protects against a Lethal Infection in a Murine Model of Pneumonic Plague. Front Microbiol. 2017 Feb 6;8:91.\|[4]LeMaire SA, et, al. Effect of Ciprofloxacin on Susceptibility to Aortic Dissection and Rupture in Mice. JAMA Surg. 2018 Sep 1;153(9):e181804. Adv Sci (Weinh). 2020 Jul 21;7(17):2001374.\|Anal Chim Acta. 15 June 2022, 340082.\|Animal Diseases. 02 November 2021.\|Appl Microbiol Biotechnol. 2022 Apr;106(7):2689-2702.\|Arab J Chem. 2024 May, 17, 5, 105745.\|bioRxiv. 2024 May 10.\|bioRxiv. 2024 Nov 06.\|Cardiovasc Toxicol. 2024 Aug 13.\|Chemosphere. 2019 Jun;225:378-387. \|EBioMedicine. 2022 Apr;78:103943.\|Front Microbiol. 2022 Feb 16;12:773664.\|Genome Biol. 2023 Apr 30;24(1):98.\|Int J Antimicrob Agents. 2018 Aug;52(2):269-271.\|iScience. 2023 Oct 5.\|J Antimicrob Chemother. 2020 Jul 1;75(7):1850-1858.\|Microb Pathog. 2024 Apr 27:106666.\|Microbiol Spectr. 2022 Apr 25:e0251821.\|Microbiol Spectr. 2022 Jan 12;e0099121.\|Molecules. 2023 Jun 8, 28(12), 4628.\|Nat Cell Biol. 2024 Jul 12.\|Nature. 2024 Aug;632(8027):1137-1144.\|NPJ Biofilms Microbiomes. 2024 Oct 28;10(1):111.\|Orebro University. 2024.\|Patent. US20200101105A1.\|PLoS Pathog. 2024 Dec 31;20(12):e1012783.\|Research Square Preprint. 2020 Jun.\|Vet Microbiol. 2024 May, 292, 110046.\|Virulence. 2024 Oct 10:2415952.\|Water Res. 2023 May 21, 120110.\|Water Res. 2024 Nov 29:271:122885.\|ACS Appl Polym Mater. 2023 Aug 29.\|bioRxiv. 2024 Jan 18.\|Animal Diseases. 02 November 2021.\|Arch Pharm Res. 2024 Dec 10.\|bioRxiv. 2024 Feb 9.\|Nat Commun. 2022 Mar 2;13(1):1116.
Smiles	O=C(C1=CN(C2CC2)C3=C(C=C(F)C(N4CCNCC4)=C3)C1=O)O
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	Bay-09867
Shipping Condition	Room temperature
Available
Manufacturer - Type	Reference compound
Manufacturer - Applications	COVID-19-immunoregulation
Manufacturer - Targets	Antibiotic; Apoptosis; Bacterial; Mitochondrial Metabolism; Reactive Oxygen Species (ROS); Topoisomerase
Shipping Temperature	Room Temperature
Storage Conditions	4°C (Powder, protect from light)
Molecular Weight	331.34
Product Description	Ciprofloxacin (Bay-09867) is a potent, orally active topoisomerase IV inhibitor. Ciprofloxacin induces mitochondrial DNA and nuclear DNA damage and lead to mitochondrial dysfunction, ROS production. Ciprofloxacin has anti-proliferative activity and induces apoptosis. Ciprofloxacin is a fluoroquinolone antibiotic, exhibiting potent antibacterial activity[1][2][3][4].
Manufacturer - Research Area	Cancer; Infection
Solubility	0.1 M HCl: 16.67 mg/mL (ultrasonic; warming; adjust pH to 2 with HCl; heat to 60°C)\|DMSO: 4.86 mg/mL (ultrasonic; warming; adjust pH to 5 with 1 M HCl; heat to 60°C)\|H2O: 6.78 mg/mL (ultrasonic; warming; adjust pH to 3 with 1 M HCl; heat to 60°C)
Manufacturer - Pathway	Anti-infection; Apoptosis; Cell Cycle/DNA Damage; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB
Isoform	Quinolone
Clinical information	Launched

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

Request product datasheet

HY-B0356-1g-safety-datasheet.pdf