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Thioredoxin reductase peptide (TFA)

Thioredoxin reductase peptide (TFA)

Item no.	HY-P1948A-10mM
Manufacturer	MedChem Express
Amount	10 mMx1 mL
Quantity options	10 mMx1 mL 10 mg 1 mg 5 mg
Category	Oncology By Cell Type Carcinoma Peptides & Proteins Cell Biology Cell Status Senescence Peptides
Type	Peptides
Specific against	other
Citations	[1]Jan YH, et al. Cross-linking of thioredoxin reductase by the sulfur mustard analogue mechlorethamine(methylbis(2-chloroethyl)amine) in human lung epithelial cells and rat lung: selective inhibition of disulfide reduction but not redox cycling. Chem Res Toxicol. 2014 Jan 21;27(1):61-75.\|[2]Valette O, et al. Biochemical Function, Molecular Structure and Evolution of an Atypical Thioredoxin Reductase from Desulfovibrio vulgaris. Front Microbiol. 2017 Sep 29;8:1855.
Smiles	OC(C(F)(F)F)=O.O=C(NCC(N[C@@H](CC(C)C)C(NCC(NCC(N[C@@H]([C@H](O)C)C(N[C@@H](CS)C(N[C@@H](C(C)C)C(N[C@@H](CC(N)=O)C(N[C@@H](C(C)C)C(NCC(N[C@@H](CS)C(N[C@@H]([C@@H](C)CC)C(N1[C@@H](CCC1)C(N[C@@H](CCCCN)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](CC2=CNC3=CC=CC=C23)N
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Shipping Condition	Cool pack
Available
Manufacturer - Type	Peptides
Manufacturer - Targets	Others
Shipping Temperature	Blue Ice
Storage Conditions	-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Molecular Weight	1617.81
Product Description	Thioredoxin reductase peptide TFA corresponds to residues 53–67 in thioredoxin reductase (TrxR), used in thioredoxin reductase research. Thioredoxin reductase acts as a reductant of disulfide-containing proteins and plays crucial role in cellular antioxidant defense[1][2].
Manufacturer - Research Area	Others
Solubility	DMSO: 50 mg/mL (ultrasonic)\|H2O: 12.5 mg/mL (ultrasonic)
Manufacturer - Pathway	Others
Clinical information	No Development Reported

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HY-P1948A-10mM-safety-datasheet.pdf