3-AQC

Item no.	ALO-A-205-5mg
Manufacturer	Alomone
CASRN	149685-89-2
Amount	5 mg
Quantity options	10 mg 25 mg 50 mg 5 mg
Category	Neuroscience Metabolism Regulation of Appetite Molecular Targets for Neuroscience Reagents & Chemicals Molecules
Type	Small Molecules
Format	Lyophilized
Specific against	other
Purity	>98%
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Shipping Condition	Room temperature
Available
Manufacturer - Type	Non Antibodies
Manufacturer - Category	S. Molecules
Manufacturer - Targets	5-HT3A channel
Country of Origin	Israel
Shipping Temperature	Shipped at room temperature. Product as supplied can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C
Storage Conditions	Storage as Solution: Up to four weeks at 4°C or three months at -20°C. - Storage after Reconstitution: The reconstituted solution can be stored at 4°C for up to 1 week. For longer periods (up to 6 months), small aliquots should be stored at -20°C. We do not recommend storing the product in working solutions for longer than a few days. Avoid multiple freeze-thaw cycles.
Molecular Weight	395, 41
Manufacturer - Format	Lyophilized powder.
Short description	An Antagonist of 5-HT3 Channels
Description	An Antagonist of 5-HT3 Channels
Reconstitution	100 mM in DMSO. Centrifuge all product preparations before use (10000 x g 5 min).
PH	7, 4
UNSPSC	41116134
Effective Concentration	1-100 µM.
Activity	3-AQC is a potent and selective 5-HT3A receptor antagonist1.
Solubility	100 mM in DMSO. Centrifuge all product preparations before use (10000 x g 5 min).
Bioassay tested	Yes
Chemical Name	3-(4-allylpiperazin-1-yl)-2-quinoxalinecarbonitrile maleate.
Scientific Background	Serotonin (5-hydroxytryptamine, 5-HT) is a monoamine neurotransmitter synthesized from the amino acid tryptophan by the enzyme tryptophan-decarboxylase. The 5-HT3 channel is a ligand gated ion channel receptor of the cys-loop channel family. It is a pentamer with five subunits surrounding a central channel1.3-AQC is a potent and selective antagonist of the 5-HT3A channel. 3-AQC is a derivative of Piperazinyquinoxaline synthetically designed to be 100 times more potent in blocking Serotonin receptors than Tropisetron.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

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ALO-A-205-5mg-safety-datasheet.pdf