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Tetrodotoxin

Tetrodotoxin

Item no.	ALO-T-500-5x1mg
Manufacturer	Alomone
CASRN	4368-28-9
Amount	5 x 1 mg
Quantity options	1 mg 5 x 1 mg
Category	Neuroscience Molecular Targets for Neuroscience Neural Adhesion Molecules Cardiovascular Research Ischemia & Reperfusion Injury Reagents & Chemicals Arrhythmias Molecules
Type	Small Molecules
Format	Lyophilized
Specific against	other
Purity	>99% (HPLC)
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Shipping Condition	Room temperature
Available
Manufacturer - Type	Non Antibodies
Manufacturer - Category	S. Molecules
Manufacturer - Targets	Various NaV Na+ channels
Country of Origin	Israel
Shipping Temperature	Shipped at room temperature. Product as supplied can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C
Storage Conditions	Storage as Solution: Up to one week at 4°C or six months at -20°C.
Molecular Weight	319, 28
Manufacturer - Format	Lyophilized Powder
Short description	A Classic Blocker of a Subset of NaV Channels
Description	TTX - A Classic Blocker of a Subset of NaV Channels
Reconstitution	Acidic buffer (pH 4.8). Centrifuge all product preparations before use (10000 x g 5 min).
PH	7, 4
UNSPSC	41116134
Origin	Tetraodon pardalis (puffer fish).
Effective Concentration	100 nM - 1 µM.
Activity	Tetrodotoxin is a potent and selective blocker of a subclass of NaV channels1, and is often used to define subclasses of NaV channels2.
Solubility	Acidic buffer (pH 4.8). Centrifuge all product preparations before use (10000 x g 5 min).
Bioassay tested	Yes
Chemical Name	Octahydro-12-(hydroxymethyl)-2-imino-5, 9:7, 10adimethano-10aH-[1, 3]dioxocino[6, 5-d]pyrimidine-4, 7, 10, 11, 12-pentol.
Scientific Background	Tetrodotoxin (TTX) is an established potent and selective blocker of some NaV channels.1 Moreover, TTX sensitivity is used to define subclasses of NaV channels.2 It is widely used both to probe NaV activity and to reduce or block excitability in neurophysiological preparations.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

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ALO-T-500-5x1mg-safety-datasheet.pdf