Comparison

L-368,899 hydrochloride

Item no. CS-0029461-25mg
Manufacturer ChemScene
Amount 25mg
Category
Type Molecules
Specific against other
ECLASS 10.1 32169090
ECLASS 11.0 32169090
UNSPSC 12000000
Similar products 160312-62-9
Available
CAS
160312-62-9
Purity
>98%
Formula
C26H43ClN4O5S2
MWt
591.23
Solubility
DMSO : 130 mg/mL (219.88 mM; Need ultrasonic)
Clinical Information
No Development Reported
Pathway
GPCR/G Protein
Target
Oxytocin Receptor
Biological Activity
L-368, 899 hydrochloride is a potent, selective, orally bioavailable, non-peptide oxytocin receptor antagonist, with IC50s of 8.9 nM and 26 nM for rat uterus and human uterus oxytocin receptor, respectively, used as a tocolytic agent. IC50 & Target: IC50: 8.9 nM (rat uterus oxytocin receptor), 26 nM (human uterus oxytocin receptor)[1] In Vitro: L-368, 899 hydrochloride is a potent, orally bioavailable, non-peptide oxytocin receptor antagonist, with IC50s of 8.9 nM and 26 nM for rat uterus and human uterus oxytocin receptor, respectively. L-368, 899 is less active on vasopressin receptor in human liver and kidney, rat liver and kidney (IC50, 510 nM, 960 nM, 890 nM, 2400 nM, respectively)[1].

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 25mg
Available: In stock
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