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Bemegride

Bemegride

Manufacturer	ChemScene
Category	Reagents & Chemicals Molecules
Type	Molecules
Specific against	other
Amount	100mg
Item no.	CS-4896-100mg
eClass 6.1	32169090
eClass 9.0	32169090
Available
Alternative Names	3-Ethyl-3-methylglutarimide; Bemegrid
CAS	64-65-3
Purity	>98%
Formula	C8H13NO2
MWt	155.19
Solubility	DMSO : >= 32 mg/mL (206.20 mM)
Clinical Information	Launched
Pathway	Neuronal Signaling; Membrane Transporter/Ion Channel
Target	GABA Receptor; GABA Receptor
Biological Activity	Bemegride is a central nervous system stimulant and antidote for barbiturate poisoning. target: GABAA receptor Bemegride has an antagonistic action on the GABAA receptor, suppressing both GABA- and pentobarbitone-evoked whole-cell currents to similar extents. [1] Long-term oral administration to the rat of barbitone, alone or together with the analeptics bemegride or pentylenetetrazol, show that the intensity of the withdrawal syndrome generally parallels the degree of associated CNS depression. [2]

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Delivery expected until 6/6/2024