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Argipressin

Argipressin

Manufacturer	ChemScene
Category	Reagents & Chemicals Molecules
Type	Molecules
Specific against	other
Amount	50mg
Item no.	CS-5742-50mg
eClass 6.1	32169090
eClass 9.0	32169090
Available
Alternative Names	Vasopressin; Arg8-vasopressin; AVP
CAS	113-79-1
Purity	>98%
Formula	C46H65N15O12S2
MWt	1084.23
Solubility	H2O : >= 360 mg/mL (332.03 mM)
Clinical Information	Launched
Pathway	Others
Target	Others
Biological Activity	Argipressin binds to the V1-vascular arginine vasopressin receptor, with a K_d value of 1.31 nM in A7r5 rat aortic smooth muscle cells. Sequence: CysTyrPheGlnAsnCysProArgGly-NH2(Disulfide bridge: Cys1-Cys6). In Vitro: Argipressin binds to the vascular arginine vasopressin receptor, V1, with a K_d value of 1.31 nM in A7r5 rat aortic smooth muscle cells. It also stimulates the intracellular release of calcium in A7r5 cells (EC₅₀=5 nM)^[1]. AVP-induced [Ca²⁺]_i signals and immunized activity against S-100 in DRG cell culture. The minimum effective concentrations of Argipressin causing [Ca²⁺]_i responses are 100 pM in non-neuronal cells in DRG culture^[2].

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Delivery expected until 6/6/2024