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GNE-140 (racemate)

GNE-140 (racemate)

Item no.	CS-5958-5mg
Manufacturer	ChemScene
Amount	5mg
Category	Reagents & Chemicals Molecules
Type	Molecules
Specific against	other
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Similar products	1802977-61-2
Available
CAS	1802977-61-2
Purity	>98%
Formula	C25H23ClN2O3S2
MWt	499.04
Solubility	DMSO : >= 34 mg/mL (68.13 mM)
Clinical Information	No Development Reported
Pathway	Metabolic Enzyme/Protease
Target	Lactate Dehydrogenase
Biological Activity	GNE-140 racemate is a LDHA inhibitor. In vitro: Acquired resistance to GNE-140 is driven by activation of the AMPK-mTOR-S6K signaling pathway, which lead to increased OXPHOS, and inhibitors targeting this pathway could prevent resistance.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 5mg

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