E 2012

Item no.	TMO-T15184-10mM
Manufacturer	TargetMol
CASRN	870843-42-8
Amount	1 mL x 10 mM (in DMSO)
Quantity options	100 mg 1 mL x 10 mM (in DMSO) 10 mg 1 mL 1 mg 25 mg 2 mg 50 mg 5 mg
Category	Reagents & Chemicals Molecules
Type	Molecules
Format	Powder
Specific against	other
Purity	0,98
Smiles	COc1cc(\C=C2/CCCN([C@@H](C)c3ccc(F)cc3)C2=O)ccc1-n1cnc(C)c1
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	870843-42-8
Shipping Condition	Cool pack
Available
Manufacturer - Targets	Gamma-secretase
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	419.49
Description	E2012 is a γ-secretase modulator (GSM). E2012 inhibits 3β-hydroxysterol Δ24-reductase (DHCR24) at the final step in the cholesterol biosynthesis. E 2012 aims at Alzheimer's disease by reduction of amyloid β-42, and induces cataract following repeated doses in the rat.
Pathways	Stem Cells\|\|\|Proteases/Proteasome\|\|\|Neuroscience

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 1 mL x 10 mM (in DMSO)

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