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Bedaquiline fumarate

Bedaquiline fumarate

Item no.	TMO-T21023-100mg
Manufacturer	TargetMol
CASRN	845533-86-0
Amount	100 mg
Quantity options	100 mg 1 mL x 10 mM (in DMSO) 10 mg 1 mL 200 mg 25 mg 2 mg 500 mg 50 mg 5 mg
Category	Reagents & Chemicals Molecules
Type	Molecules
Specific against	other
Purity	99.77%
Citations	Ndjeka N, Schnippel K, Master I, Meintjes G, Maartens G, Romero R, Padanilam X, Enwerem M, Chotoo S, Singh N, Hughes J, Variava E, Ferreira H, Te Riele J, Ismail N, Mohr E, Bantubani N, Conradie F. High treatment success rate for multidrug-resistant and extensively drug-resistant tuberculosis using a bedaquiline-containing treatment regimen. Eur Respir J. 2018 Oct 25. pii: 1801528. doi: 10.1183/13993003.01528-2018. [Epub ahead of print] PubMed PMID: 30361246.
Smiles	OC(=O)\C=C\C(O)=O.COc1nc2ccc(Br)cc2cc1[C@@H](c1ccccc1)[C@@](O)(CCN(C)C)c1cccc2ccccc12
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	R-403323, R 403323, R403323, TMC 207, TMC207, TMC-207
Shipping condition	Cool pack
Available
Manufacturer - Targets	Antibiotic\|\|\|Antibacterial
Shipping Temperature	cool pack
Storage Conditions	-20°
Molecular Weight	671, 59
Target names or alias	R 403323 , R-403323 , R403323 , TMC 207 , TMC-207 , TMC207
Description	Bedaquiline fumarate (TMC207), a diarylquinoline antibiotic that targets ATP synthase, is effective for the treatment of Mycobacterium tuberculosis infections. It blocks the proton pump for ATP synthase of mycobacteria. It is the first member of a new class of drugs called diarylquinolines.
Pathways	Microbiology/Virology

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Amount: 100 mg

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