Comparison

Bedaquiline fumarate

Manufacturer TargetMol
Category
Type Molecules
Specific against other
Amount 25mg
Item no. TMO-T21023-25mg
Approximate Leadtime 1-2 Weeks
eClass 6.1 32169090
eClass 9.0 32169090
Available
purity
99.77%
SMILES
O[C](CCN(C)C)(C1=C2C=CC=CC2=CC=C1)[CH](C3=CC4=CC(Br)=CC=C4N=C3OC)C5=CC=CC=C5.O=C(O)/C=C/C(O)=O
formula
C36H35BrN2O6
MolWt
671.59
Pathway
Microbiology/Virology
Target
Antibiotic
Bioactivity
Bedaquiline fumarate, a diarylquinoline antibiotic that targets ATP synthase, is effective for the treatment of Mycobacterium tuberculosis infections. It blocks the proton pump for ATP synthase of mycobacteria. It is the first member of a new class of drugs called diarylquinolines.
Reference
Ndjeka N, Schnippel K, Master I, Meintjes G, Maartens G, Romero R, Padanilam X, Enwerem M, Chotoo S, Singh N, Hughes J, Variava E, Ferreira H, Te Riele J, Ismail N, Mohr E, Bantubani N, Conradie F. High treatment success rate for multidrug-resistant and extensively drug-resistant tuberculosis using a bedaquiline-containing treatment regimen. Eur Respir J. 2018 Oct 25. pii: 1801528. doi: 10.1183/13993003.01528-2018. [Epub ahead of print] PubMed PMID: 30361246.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

Amount: 25mg
Available: In stock
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