PN401

Manufacturer	TargetMol
Category	Molecule
Type	Molecules
Specific against	other
Amount	1g
Item no.	TMO-T21327-1g
Approximate Leadtime	1-2 Weeks
eClass 6.1	32169090
eClass 9.0	32169090
Available
SMILES	O=C(C=CN1[CH]2[CH](OC(C)=O)[CH](OC(C)=O)[CH](COC(C)=O)O2)NC1=O
formula	C15H18N2O9
MolWt	370.31
Bioactivity	PN-401 is a synthetic uridine pro-drug that is converted to uridine in vivo. Uridine, a pyrimidine nucleotide, has been used in a variety of diseases including depressive disorders and inherited myopathies.
Reference	Saydoff, Joel A.; Garcia, Rolando A. G.; Browne, Susan E.; Liu, Liansheng; Sheng, Jin; Brenneman, Denise; Hu, Zhongyi; Cardin, Sylvain; Gonzalez, Alexis; von Borstel, Reid W.; Gregorio, Jason; Burr, Holly; Beal, M. Flint. Oral uridine pro-drug PN401 is neuroprotective in the R6/2 and N171-82Q mouse models of Huntington's disease. Neurobiology of Disease (2006), 24(3), 455-465. CODEN: NUDIEM ISSN:0969-9961. CAN 146:266494 AN 2006:1245538

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Request Data Sheet

TMO-T21327-1g-datasheet.pdf

TMO-T21327-1g-safety-datasheet.pdf