Comparison

PN401

Manufacturer TargetMol
Category
Type Molecules
Specific against other
Amount 1g
Item no. TMO-T21327-1g
Approximate Leadtime 1-2 Weeks
eClass 6.1 32169090
eClass 9.0 32169090
Available
SMILES
O=C(C=CN1[CH]2[CH](OC(C)=O)[CH](OC(C)=O)[CH](COC(C)=O)O2)NC1=O
formula
C15H18N2O9
MolWt
370.31
Bioactivity
PN-401 is a synthetic uridine pro-drug that is converted to uridine in vivo. Uridine, a pyrimidine nucleotide, has been used in a variety of diseases including depressive disorders and inherited myopathies.
Reference
Saydoff, Joel A.; Garcia, Rolando A. G.; Browne, Susan E.; Liu, Liansheng; Sheng, Jin; Brenneman, Denise; Hu, Zhongyi; Cardin, Sylvain; Gonzalez, Alexis; von Borstel, Reid W.; Gregorio, Jason; Burr, Holly; Beal, M. Flint. Oral uridine pro-drug PN401 is neuroprotective in the R6/2 and N171-82Q mouse models of Huntington's disease. Neurobiology of Disease (2006), 24(3), 455-465. CODEN: NUDIEM ISSN:0969-9961. CAN 146:266494 AN 2006:1245538

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

Amount: 1g
Available: In stock
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