Comparison

Finerenone

Manufacturer TargetMol
Category
Type Molecules
Specific against other
Amount 25mg
Item no. TMO-T21395-25mg
Approximate Leadtime 1-2 Weeks
eClass 6.1 32169090
eClass 9.0 32169090
Available
purity
99.65%
SMILES
O=C(C1=C(C)NC2=C(C(OCC)=NC=C2C)[CH]1C3=CC=C(C#N)C=C3OC)N
formula
C21H22N4O3
MolWt
378.43
Pathway
Endocrinology/Hormones
Target
Glucocorticoid Receptor
Bioactivity
Finerenone is a third-generation, selective, and orally available nonsteroidal mineralocorticoid receptor (MR) antagonist with IC50 of 18 nM for the treatment of chronic heart failure. Finerenone displays excellent selectivity versus glucocorticoid receptor (GR), androgen receptor (AR), and progesterone receptor (>500-fold).
Reference
George L Bakris , Rajiv Agarwal , et al.Effect of Finerenone on Albuminuria in Patients With Diabetic Nephropathy: A Randomized Clinical Trial.JAMA. 2015 Sep 1; 314(9):884-94.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

Amount: 25mg
Available: In stock
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