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BMS202 hydrochloride (1675203-84-5(free base))

BMS202 hydrochloride (1675203-84-5(free base))

Item no.	TMO-T4696-1mg
Manufacturer	TargetMol
CASRN	2089334-95-0
Amount	1 mg
Quantity options	100 mg 1 mL x 10 mM (in DMSO) 10 mg 1 mg 1 mL 25 mg 2 mg 50 mg 5 mg
Category	Reagents & Chemicals Molecules
Type	Molecules
Format	Powder
Specific against	other
Purity	0,98
Smiles	Cl.COc1nc(OCc2cccc(c2C)-c2ccccc2)ccc1CNCCNC(C)=O
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	PD-1/PD-L1 inhibitor 2 hydrochloride
Shipping Condition	Cool pack
Available
Manufacturer - Targets	PD-1/PD-L1
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	455.97
Description	BMS202 hydrochloride (1675203-84-5(free base)) (PD-1/PD-L1 inhibitor 2 hydrochloride) is a small-molecule PD-1/PD-L1 interaction inhibitor (IC50: 18 nM). Biophysical studies demonstrate that BMS202 binds directly to PD-L1. Binding of BMS202 promotes PD-L1 dimerisation and blocks the PD-L1/ PD1 interaction.
Pathways	Cell Cycle/Checkpoint\|\|\|Apoptosis\|\|\|Immunology/Inflammation

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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