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BMS202 hydrochloride (1675203-84-5(free base)) European Partner

Item no. TMO-T4696-1ml
Manufacturer TargetMol
CASRN 2089334-95-0
Amount 1 mL
Quantity options 100 mg 1 mL x 10 mM (in DMSO) 10 mg 1 mg 1 mL 25 mg 2 mg 50 mg 5 mg
Category
Type Chemicals
Specific against other
Smiles Cl.COc1nc(OCc2cccc(c2C)-c2ccccc2)ccc1CNCCNC(C)=O
ECLASS 10.1 32160000
ECLASS 11.0 32160000
UNSPSC 12000000
Alias PD-1/PD-L1 inhibitor 2 hydrochloride
Shipping Condition Cool pack
Available
Manufacturer - Targets
PD-1/PD-L1
Shipping Temperature
Cool pack
Storage Conditions
-20
Molecular Weight
455.97
Description
BMS202 hydrochloride (1675203-84-5(free base)) (PD-1/PD-L1 inhibitor 2 hydrochloride) is a small-molecule PD-1/PD-L1 interaction inhibitor (IC50: 18 nM). Biophysical studies demonstrate that BMS202 binds directly to PD-L1. Binding of BMS202 promotes PD-L1 dimerisation and blocks the PD-L1/ PD1 interaction.
Pathways
Cell Cycle/Checkpoint|||Apoptosis|||Immunology/Inflammation

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 1 mL
Available: In stock
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