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PS-1145

PS-1145

Item no.	V0753-10mg
Manufacturer	InvivoChem LLC
CASRN	431898-65-6
Amount	10 mg
Quantity options	100 mg 250 mg 25 mg 500 mg 50 mg 5 mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	431898-65-6
Available
Description	InvivoChem Cat #:V0753CAS #:431898-65-6Purity >=98% Description: PS-1145 (PS1145) is a novel, potent and specific IKK (IkappaB kinase) inhibitor with anticancer activity. It inhibits IKK with an IC50 of 88 NM. PS 1145 exhibits excellent in vivo antitumor efficacy in rats bearing DMBA-induced skin tumors. rats bearing DMBA-induced skin tumors. References: J Biol Chem. 2002 May 10; 277(19):16639-47. Related CAS: 1049743-58-9 (HCl) 431898-65-6 (free base)
Molecular Weight (MW)	322.75
Formula	C17H11ClN4O
CAS No.	431898-65-6 (free base);
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: 64 mg/mL (198.3 mM)
	Water: < 1 mg/mL
	Ethanol: 2 mg/mL warmed (6.2 mM)
Other info	Chemical Name: N-(6-chloro-9H-pyrido[3, 4-b]indol-8-yl)nicotinamide InChi Key: JZRMBDHPALEPDM-UHFFFAOYSA-N InChi Code: InChI=1S/C17H11ClN4O/c18-11-6-13-12-3-5-20-9-15(12)21-16(13)14(7-11)22-17(23)10-2-1-4-19-8-10/h1-9, 21H, (H, 22, 23) SMILES Code: O=C(C1=CC=CN=C1)NC2=CC(Cl)=CC3=C2NC4=C3C=CN=C4
Synonyms	PS 1145; PS1145; PS-1145;

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 10 mg

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