Comparison

Pimobendan

Item no. V0782-100mg
Manufacturer InvivoChem LLC
CASRN 74150-27-9
Amount 100 mg
Quantity options 1 g 250 mg 2 g 500 mg 5 g
Category
Type Biochemicals
Specific against other
ECLASS 10.1 32160490
ECLASS 11.0 32160490
UNSPSC 12000000
Alias 74150-27-9
Available
Description
InvivoChem Cat #:V0782CAS #:74150-27-9Purity >=98%

Description: Pimobendan (UD-CG115; UDCG115; Trade names Vetmedin, Acardi), a veterinary medication approved to treat CHF-congestive heart failure in dogs, is a potent and selective inhibitor of phosphodiesterase PDE3 with positive inotropic and vasodilator effects. It inhibits PDE3 with an IC50 of 0.32 uM.

Description:

References: J Cardiovasc Pharmacol. 1991 Jul; 18(1):17-27; J Am Coll Cardiol. 1999 Apr; 33(5):1400-7.

References:

Related CAS: 77469-98-8 (HCl); 118428-37-8 (-)- Pimobendan

Molecular Weight (MW)
334.37
Formula
C19H18N4O2
CAS No.
74150-27-9 (free base);
Storage
-20C for 3 years in powder form
-80C for 2 years in solvent
Solubility (In vitro)
DMSO: 67 mg/mL (200.4 mM)
Water:< 1 mg/mL
Ethanol: 5 mg/mL (14.95 mM)
Solubility (In vivo)
0.5% methylcellulose: 30mg/mL
Synonyms
UD-CG-115; UD-CG115; UD CG115; UD-CG 115; Pimobendan; pimobendane. Trade names: Vetmedin and Acardi

Chemical Name: 3-[2-(4-methoxyphenyl)-3H-benzimidazol-5-yl]-4-methyl-4, 5-dihydro-1H-pyridazin-6-one

InChi Key: GLBJJMFZWDBELO-UHFFFAOYSA-N

InChi Code: InChI=1S/C19H18N4O2/c1-11-9-17(24)22-23-18(11)13-5-8-15-16(10-13)21-19(20-15)12-3-6-14(25-2)7-4-12/h3-8, 10-11H, 9H2, 1-2H3, (H, 20, 21)(H, 22, 24)

SMILES Code: O=C1CC(C)C(C2=CC=C3C(NC(C4=CC=C(OC)C=C4)=N3)=C2)=NN1

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 100 mg
Available: In stock
available

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