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Pimobendan

Pimobendan

Item no.	V0782-1g
Manufacturer	InvivoChem LLC
CASRN	74150-27-9
Amount	1 g
Quantity options	100 mg 250 mg 2 g 500 mg 5 g
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V0782CAS #:74150-27-9Purity >=98% Description: Pimobendan (UD-CG115; UDCG115; Trade names Vetmedin, Acardi), a veterinary medication approved to treat CHF-congestive heart failure in dogs, is a potent and selective inhibitor of phosphodiesterase PDE3 with positive inotropic and vasodilator effects. It inhibits PDE3 with an IC50 of 0.32 uM. Description: References: J Cardiovasc Pharmacol. 1991 Jul; 18(1):17-27; J Am Coll Cardiol. 1999 Apr; 33(5):1400-7. References: Related CAS: 77469-98-8 (HCl); 118428-37-8 (-)- Pimobendan
Molecular Weight (MW)	334.37
Formula	C19H18N4O2
CAS No.	74150-27-9 (free base);
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: 67 mg/mL (200.4 mM)
	Water:< 1 mg/mL
	Ethanol: 5 mg/mL (14.95 mM)
Solubility (In vivo)	0.5% methylcellulose: 30mg/mL
Synonyms	UD-CG-115; UD-CG115; UD CG115; UD-CG 115; Pimobendan; pimobendane. Trade names: Vetmedin and Acardi Chemical Name: 3-[2-(4-methoxyphenyl)-3H-benzimidazol-5-yl]-4-methyl-4, 5-dihydro-1H-pyridazin-6-one InChi Key: GLBJJMFZWDBELO-UHFFFAOYSA-N InChi Code: InChI=1S/C19H18N4O2/c1-11-9-17(24)22-23-18(11)13-5-8-15-16(10-13)21-19(20-15)12-3-6-14(25-2)7-4-12/h3-8, 10-11H, 9H2, 1-2H3, (H, 20, 21)(H, 22, 24) SMILES Code: O=C1CC(C)C(C2=CC=C3C(NC(C4=CC=C(OC)C=C4)=N3)=C2)=NN1

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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