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calcitriol-d6

calcitriol-d6

Item no.	V29310-500ug
Manufacturer	InvivoChem LLC
CASRN	78782-99-7
Amount	500 ug
Quantity options	10 mg 1 mg 2 mg 5 mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V29310CAS #:78782-99-7Purity >=98% Description: Calcitriol D6 is the deuterated form of Calcitriol (1, 25-Dihydroxyvitamin D3; Rocaltrol), which is is the metabolically/hormonally active form of vitamin D and a vitamin D receptor (VDR) agonist. Calcitriol is converted to metabolites more potent and rapidly acting than other forms of Vitamin D. Calcitriolhas played an important role in mineral and skeletal homeostasis byregulating the differentiation, growth and the function of the cellimmune system. References: 1. Canalejoet al (2000) The in vitro effect of calcitriol on parathyroid cellproliferation and apoptosis. J.Am.Soc.Nephrol. 11 1865. Beer and Myrthue(2004) 2. Calcitriol in cancer treatment: from the lab to the clinic. Mol.Cancer Ther. 3 373. 3. Nijenhuis et al (2006) The novel vitamin D analog ZK191784 as an intestine-specific vitamin D antagonist. FASEB J. 20 1589. 4. KrishnanAV, Swami S, Feldman D.Equivalent anticancer activities of dietaryvitamin D and calcitriol in an animal model of breast cancer: Importanceof mammary CYP27B1 for treatment and prevention.J Steroid Biochem MolBiol. 2012 Aug 23. 5. AlkharfyKM, Al-Daghri NM, Yakout SM, Ahmed M.Calcitriol AttenuatesWeight-Related Systemic Inflammation and Ultrastructural Changes of theLiver in a Rodent Model.Basic Clin Pharmacol Toxicol. 2012 Aug 21.

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 500 ug

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